SAN ANTONIO, Texas - Zack Eskridge and Andy Tanner connected three times for touchdowns as No. 24 Midwestern State rolled to a 49-7 win over Incarnate Word Saturday night at Benson Stadium.

Eskridge passed for 340 yards and four touchdowns, while Tanner had five catches for a career-high 146 yards including scores of 80, 33 and 26 yards.

Incarnate Word (1-2) scored the first touchdown against the Mustangs this season when Thomas Specia hit Todd Walker on an 11-yard hookup 4 minutes into the third quarter. The TD broke a string of 14 consecutive quarters without allowing a touchdown for the Mustangs.

The Mustangs rolled out to a 21-0 halftime lead as Eskridge hit Tanner on a slip screen for an 80-yard TD  in the first quarter, then found Sasan Faradineh on a 5-yard score to begin the second quarter before reconnected with Tanner on a 33-yard hookup in the final minute of the half.

Midwestern answered the Cardinals' lone score of the game with four-straight scores including another Eskridge-to-Tanner strike good for 26 yards before BeeJay Mathis, Ben McMahan and Brandon Minor closed out the scoring with rushing touchdowns for the Mustangs.

The Mustangs, who improved to 4-0 for the fourth-straight season, take on Angelo State in their Lone Star Conference South Division opener Saturday night at Angelo Stadium. Kickoff is set for 6 p.m.